High throughput rAB services
With the increasing demand for research antibody, Biointron has launched high throughput recombinant antibody production services to support antibody drug screening. High throughput recombinant antibody production services, using CHO cells or HEK293 cells as host cells, to produce recombinant antibodies with high throughput and quality through standardized antibody fast antibody expression technology platforms.
|Customer provides||Scale and format||Premium service details||Timeline||Deliverables|
|Electronic sequence or hybridoma||0.1 mg to 10 grams, any IgG species or subtype||Gene synthesis|
Buffer exchange (PBS)
Purity >98% (SDS-PAGE)
Monomer purity >95% (HPLC)
Endotoxin < 1EU/mg
|2-3 weeks||Purified antibody|
Advantages of recombinant antibodies
Compared with the traditional monoclonal antibody and polyclonal antibody, recombinant antibody has several advantages:
Consistency and repeatability are higher
The quality of antibody production is controlled by a unique set of genes, and the difference between batches of antibodies is very small. Some problems in the preparation of hybridoma cells, such as gene loss, gene mutation and cell drift, can be avoided.
Sensitivity and specificity are stronger
Engineering improves antibody specificity and sensitivity. The selection process required for cloning occurs at the stage of hybridoma cells and recombinant clones, which allows us to select the optimal antibody quality.
High throughput, large scale, fast speed
Compared with the conventional monoclonal technique, antibody expression can be performed on a single clone of 100+ at a shorter time in any scale. We can deliver custom antibodies within two weeks.
High throughput production with animal-free culture
Once the antibody producing gene is isolated, no animal in vitro production can be achieved.